Summary: We compare the side effects and drug effectiveness of Letrozole and Tamoxifen citrate. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Letrozole is used to treat certain types of breast cancer in women who have already stopped menstruating (postmenopausal). Dizzy 2. It would take me 1.5 hours to fall asleep and could not sleep for more 2 hrs before waking back up. The phase IV clinical study is created by eHealthMe based on reports of 24,728 people who have side effects when taking Letrozole from the FDA, and is updated regularly. Feeling Weak 6. It is also used for women who have already had other cancer treatments (eg, tamoxifen). The following side effects are common (occurring in greater than 30%) for patients taking Letrozole: Hot flashes; High cholesterol; These side effects are less common side effects (occurring in about 10-29%) of patients receiving Letrozole: Arthralgias (bone and joint pain) Night sweats; Weight gain; Nausea; Not all side effects are listed above. The use of the eHealthMe site and its content is at your own risk. You may have sweats and then feel cold and clammy. Dental and oral side effects can make it difficult to eat, talk, chew, or swallow. Key words: letrozole, macular oedema, multifocal electroretinogram, ranibizumab Letrozole (Femara®, Novartis) is an oral non-steroidal aromatase inhibitor, more effective than tamoxifen and is used as a first-line adjuvant therapy for post-surgical treatment of hormonally responsive breast cancer.1 Ophthalmic side effects, such as The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 92,833 people who take Letrozole and Lupron depot, and is updated regularly. Selected from data included with permission and copyrighted by First Databank, Inc. I am so sorry you are experiencing problems. These side effects may go away during treatment as your body adjusts to the medicine. My pharmacist gave me a list of side effects for Letrozole and I dont believe damage to healthy teeth was one. Google "Trigeminal Neuropathy", and you can read the information regarding the mouth issues associated with this problem. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Feeling tired or weak. Start now, it's free and anonymous. This side effect can be very troubling for some women. Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. Side effects requiring immediate medical attention. The study is created by eHealthMe based on reports of 21,046 people who have side effects when taking Letrozole from the FDA, and is updated regularly. Head Pain 7. The following side effects have been reported by at least 1% of people taking this medication. Sometimes the combination of meds can magnify the side effect. Common drugs people take besides Letrozole *: Common side effects people have besides Tooth loss *: Check whether Tooth loss is caused by a drug or a condition. On eHealthMe, our answer is simple: run your own phase IV clinical trial. Cinderella59 I know chemo does damage healthy teeth, nails, and of course cause hair loss. PRECAUTIONS: Before taking letrozole, tell your doctor or pharmacist if you are allergic to it; or to anastrozole ; or if you have any other allergies . The side effects listed below are not experienced by everyone who takes this medication. Applies to letrozole: oral tablet. Tooth loss is found among people who take Letrozole, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. Side effects not requiring immediate medical attention. Other drugs that have the same active ingredients (e.g. Salivary glands make saliva. To our To our knowledge letrozole induced linear drug eruption has not been described in previous reports. Side effects of Femara. Tips to help manage the side effects are included. So how do you know what your drugs can do to you? Letrozole has active ingredients of letrozole. Posted By Anonymous in askapatient.com on January 10, 2010 @ 12:00 am “ Side Effects: Initially there was some hair thinning but after almost a year my hair is suddenly shedding like mad. Flushes may last from a few seconds up to 10 minutes. Femara is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years.Femara is available in generic form. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. The study uses data from the FDA. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. eHealthMe is studying from 12,550 Tooth loss patients now. These side effects may go away during treatment as your body adjusts to the medicine. 24,728 people reported to have side effects when taking Letrozole. It is a nagging pain that is always there. High Cholesterol 8. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Things to remember when you fill your prescription. Some side effects of palbociclib may occur that usually do not need medical attention. I am wondering if anyone else has had problems with this, especially with your front bottom teeth. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Feel Like Throwing Up 5. If experienced, these tend to have a Less Severe expression 1. Visible Water Retention 11. However, many people have no side effects or only have minor side effects. By design, clinical trials use only a small and selected set of people, and are conducted in a highly controlled environment. All information is observation-only, does not establish causal relationship, and has not been supported by scientific studies or clinical trials unless otherwise stated. * Approximation only. Drug-Induced Hot Flash 3. Tooth loss is found among people who take Letrozole, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. Will you have Periventricular Leukomalacia with Hiv Infection? 1. It is recommended that patients use the information presented as a part of a broader decision-making process. I have tried using Sensodyne toothpaste, and the dentist has given me a paste to use at night which helps with sensitivity. Dosage of drugs is not considered in the study. Femara; Descriptions. Tooth loss has been reported by people with hiv infection, osteoporosis, metastases to bone, pain, rheumatoid arthritis. It is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years.. Letrozole may also be used for purposes not listed in this … One of many side effects I have encountered since I started taking Femara 90 days ago is problems with teeth sensitivity. Femara is a non-steroidal aromatase inhibitor (lowers estrogen production) used to treat breast cancer in postmenopausal women. The study is created by eHealthMe based on reports of 21,046 people who have side effects when taking Letrozole from the FDA, and is updated regularly. Among them, 93 people (0.38%) have Tooth loss. letrozole related tooth extraction cgs 20267 related tooth extraction * Warning : The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be … Fortunately, with good care, you and your doctor can lower the risk It is very unlikely that you will have all of these side effects, but you might have some of them at the same time. All drugs may cause side effects. © 2005 - 2019 WebMD LLC. If you lose your appetite, it may help to take your tablet with food. We haven't listed all the side effects. eruption due to letrozole is one of the side effects that known to be developed by this drug. Weight Gain DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. What are the side effects of letrozole? Hot flushes are a common side effect of this treatment. Most people who take letrozole will have had surgery, radiotherapy or sometimes chemotherapy to treat their breast cancer first. The phase IV trial will monitor drug safety outcomes that are personalized to your gender and age (0-99+). Druginformer Identified Side Effects: Back pain, Pain, Anger, Arthritis, Alopecia, Adverse event, Apathy, Tooth malformation, Emotional distress. Common side effects of Femara include: hot flashes, ; warmth in your face or chest, Hot flashes, hair loss, joint/bone/muscle pain, tiredness, unusual sweating, nausea, diarrhea, dizziness, and trouble sleeping may occur. Tooth extraction is found among people who take Letrozole, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. Tooth loss and drugs with ingredients of letrozole, Ashwagandha and N-Acetyl-L-Cysteine drug interaction. For the Consumer. If your appetite increases it may affect your weight. Some side effects of anastrozole may occur that usually do not need medical attention. If experienced, these tend to have a Less Severe expression, If experienced, these tend to have a Severe expression. Comment: I took Letrozole for 4 months, my side effects got worse each month. Headache. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Decreased Calcification Or Density Of Bone, Fluid Retention In The Legs, Feet, Arms Or Hands, A Significant Type Of Allergic Reaction Called Anaphylaxis, A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome, A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis, A Type Of Allergic Reaction Called Angioedema, Erythema Multiforme, A Type Of Allergic Skin Reaction, Inflammation Of The Liver Called Hepatitis, Obstruction Of A Blood Vessel By A Blood Clot, Clouding Of The Lens Of The Eye Called Cataracts. All articles are thoroughly researched and reference high-quality studies and information to support the subject matter. WebMD does not provide medical advice, diagnosis or treatment. If you struggle to maintain a healthy weight, ask your GP or specialist about being referred to a dietitian. Most likely your drugs were not studied in clinical trials based on patients like you. What are some other side effects of Letrozole? The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 64,202 people who take Letrozole and Tamoxifen citrate, and is updated regularly. See below for a comprehensive list of adverse effects. During a flush, your neck and face may feel warm and look red. See below for a comprehensive list of adverse effects. Other side effects include: myalgia. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. It's free, simple and personalized to your gender and age (0-99+). The most common side-effects of treatment are hot flushes, sweating, joint pain, and feeling tired. • Letrozole is usually well tolerated and serious side effects are rare. Some reports may have incomplete information. Excessive Sweating 4. Different individuals may respond to medication in different ways. Temporary Redness Of Face And Neck 10. The recommended dose of letrozole is 2.5 mg once daily. Start now. Dizziness. You may find eating small frequent meals or snacks helps keep up your food intake. Continuing or severe nervousness 2. cough 3. dizziness or lightheadedness 4. fainting 5. fast heartbeat 6. heart attack 7. increased sweating 8. nausea 9. pain in the chest, groin, or legs, especially the calves 10. severe and sudden, unexplained troubled breathing 11. severe, sudden headache 12. slurred speech 13. sudden loss of coordination 14. sudden, severe weakness or numbness in the arm or leg 15. swollen glands 16. vaginal bleeding 17. vision changes All rights reserved. Side effects not requiring immediate medical attention. The symptoms are a constant "tooth" pain in mainly my upper gum area on the left side of my face. All rights reserved. You may report side effects to Health Canada at 1-866-234-2345. Citalopram Hydrobromide: 23 people, 24.73%, Osteonecrosis Of Jaw (death of bone of jaw): 47 people, 50.54%, Tooth Abscess (pus formation in tooth): 44 people, 47.31%, Anaemia (lack of blood): 42 people, 45.16%, Urinary Tract Infection: 42 people, 45.16%, Cellulitis (infection under the skin): 40 people, 43.01%, Rectal Haemorrhage (bleeding from anus): 35 people, 37.63%, Night Sweats (sweating in night): 33 people, 35.48%, Purulent Discharge (discharge that contains pus): 30 people, 32.26%, Hypoaesthesia (reduced sense of touch or sensation): 29 people, 31.18%, Metastases To Bone (cancer spreads to bone): 29 people, 31.18%, Osteomyelitis (infection of bone): 27 people, 29.03%, Toothaches (tooth pain): 25 people, 26.88%, Gingival Pain (gum pain): 24 people, 25.81%, Oral Disorder (mouth disease): 24 people, 25.81%, Fatigue (feeling of tiredness): 24 people, 25.81%, Mitral Valve Prolapse (heart's mitral valve doesn't work well): 23 people, 24.73%, White Blood Cell Count Increased: 23 people, 24.73%, Intervertebral Disc Protrusion (spinal disc protrusion): 23 people, 24.73%, Hypoaesthesia Oral (reduced sense of touch or sensation in mouth): 23 people, 24.73%, Herniated Nucleus Pulposus (Slipped Disk): 23 people, 24.73%, Haemorrhoids (a swollen vein or group of veins in the region of the anus): 23 people, 24.73%, Nuclear Magnetic Resonance Imaging Abnormal: 23 people, 24.73%, Exostosis (formation of new bone on the surface of a bone): 23 people, 24.73%, Areflexia (absence of a reflex): 23 people, 24.73%, Neuralgia (pain in one or more nerves): 23 people, 24.73%, Wound Infection Staphylococcal: 23 people, 24.73%, Osteitis (a general term for inflammation of bone): 23 people, 24.73%, Spinal Osteoarthritis (joint cartilage loss in spine): 23 people, 24.73%, Oral Mucosal Exfoliation (removal of mucous membrane of mouth): 23 people, 24.73%, Hypercalcaemia (elevated calcium (ca+) level in the blood): 23 people, 24.73%, Metastases To Bone (cancer spreads to bone): 16 people, 17.20%, Anaemia (lack of blood): 13 people, 13.98%, Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 12 people, 12.90%, Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 12 people, 12.90%, Gout (uric acid crystals building up in the body): 12 people, 12.90%, Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 2 people, 2.15%, Bipolar Disorder (mood disorder): 1 person, 1.08%, Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 1.08%, Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 1.08%, Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 1.08%, Flatulence (flatus expelled through the anus): 1 person, 1.08%, Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 1.08%, Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 1.08%, Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 1.08%, Neuropathy Peripheral (surface nerve damage): 1 person, 1.08%, Hypotension (abnormally low blood pressure): 1 person, 1.08%, Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 1.08%. Along with its needed effects, letrozole may cause some unwanted effects. generic drugs) are not considered. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Side effects are listed in the following table in the order in which they may occur. © 2021 eHealthMe.com. Common side effects of Femara include: bone fracture, arthralgia, edema, dizziness, fatigue, hypercholesterolemia, osteoporosis, and flushing. compared to not taking Femara after 5 years of tamoxifen. Joint Pain 9. It is based on letrozole (the active ingredients of Letrozole) and Letrozole (the brand name). Although not all of these side effects may occur, if they do occur they may need medical attention. eHealthMe is studying from 25,026 Letrozole users now. Summary: We compare the side effects and drug effectiveness of Letrozole and Lupron depot. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. It is often used in breast cancer. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. How often and how severe the side effects are can vary from person to person. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Hot flashes. Listen to the Cancer.Net Podcast: Dental Health During Cancer Treatment, adapted from this content.Many cancer treatments have side effects that affect a person's mouth, teeth, and salivary glands. Letrozole is a medicine used for treating breast cancer.It can also help prevent breast cancer coming back. Because Femara lowers the amount of estrogen in the body, less estrogen reaches bone cells, which can lead to bone thinning and weakening and a higher-than-average risk of broken bones. Fi… These can occur in more than 1 in 10 women who take letrozole. Running one of the largest drug safety studies in the world, eHealthMe is able to enable everyone to run personal clinical trial. Letrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.. Letrozole is used to treat breast cancer in postmenopausal women. It is mainly prescribed for women who have been through the menopause and have a type of cancer called "hormone-dependent" breast cancer.. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect.
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